Treatment as prevention--a double hat-trick.
نویسنده
چکیده
208 www.thelancet.com Vol 378 July 16, 2011 4 Family Health International. FHI statement on the FEM-PrEP HIV prevention study. http://minilicious.wordpress.com/2011/04/18/fh i-statement-onthe-fem-prep-hiv-prevention-study/ (accessed June 28, 2011). 5 Abdool Karim SS, Kashuba A, Werner L, Abdool Karim Q. Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women. Lancet 2011; 378: 279–81. 6 Hendrix C, Minnis A, Guddera V, et al. MTN-001: a phase 2 cross-over study of daily oral and vaginal TFV in healthy, sexually active women results in signifi cantly diff erent product acceptability and vaginal tissue drug concentrations. 18th Conference on Retroviruses and Opportunistic Infections. Boston, MA, USA. Feb 27–March 22, 2011. 35LB (abstr). 7 Patterson KB, Prince HA, Kraft E, et al. Exposure of extracellular and intracellular tenofovir and emtricitabine in mucosal tissues after a single of fi xed-dose TDF/FTC: implications for pre-exposure HIV prophylaxis (PrEP). XVIII International AIDS Conference; Vienna, Austria. July 18–23, 2010. THBS0305 (abstr). 8 UNAIDS. UNAIDS report on the global AIDS epidemic 2010. Geneva: joint United Nations programme on HIV/AIDS. 2010. http://www.unaids.org/ globalreport/ (accessed Feb 11, 2011). 9 Paltiel AD, Freedberg KA, Scott CA, et al. HIV preexposure prophylaxis in the United States: impact on lifetime infection risk, clinical outcomes, and cost-eff ectiveness. Clin Infect Dis 2009; 48: 806–15. 10 Walensky R, Park J-E, Wood R, et al. Cost eff ectiveness of PrEP for HIV infection in South Africa. 18th Conference on Retroviruses and Opportunistic Infections. Boston, MA, USA. Feb 27–March 22, 2011. 37LB (abstr).
منابع مشابه
Pleiotropic Functions of the Chromodomain-Containing Protein Hat-trick During Oogenesis in Drosophila melanogaster
Chromatin-remodeling proteins have a profound role in the transcriptional regulation of gene expression during development. Here, we have shown that the chromodomain-containing protein Hat-trick is predominantly expressed within the oocyte nucleus, specifically within the heterochromatinized karyosome, and that a mild expression is observed in follicle cells. Colocalization of Hat-trick with He...
متن کاملTetanus Disease (Its Prevention and Treatment)
Nach dem kurzen Bericht ueber die Geschichte van Tetanus; haben wir in diesern Artikel versucht,ueber die Epedirniologie, Pathophisiologie,Aethiologie und die Frueh-und Spaet-Sympptome von dieser gcfahrlichen Krankheit,die einen Durchschnitt von 35% Mortalitaet hat,zu berichten. In disern Artikel legen wir vi.ei wert,besoaders ueber die The·.rapie 1md der Prophyla.xe. Unc:I wii' hal)en bed...
متن کاملThe HAT TRICK programme for improving physical activity, healthy eating and connectedness among overweight, inactive men: study protocol of a pragmatic feasibility trial
INTRODUCTION Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. Many health promotion programmes hold little appeal to men and consequently fa...
متن کاملتاثیر کلاه بر هیپوکلسمی ناشی از فتوتراپی در نوزادان ایکتریک
Background & Aim: Phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia in neonates. However, this treatment modality may itself result in the development of some complications. A lesser-known complication of the phototherapy is hypocalcemia. Some studies reported hypocalcemia accompanied by a decrease in serum melatonin concentration, yet this effect c...
متن کاملSusan McHugh Animal Farm ’ s Lessons for Literary ( and ) Animal Studies
Everybody knows the disappearing animal trick: rabbit goes into the hat, magician waves wand, and presto! The magician displays an empty hat. Simplistic though it sounds, this old act illustrates how literary critics historically have rendered the animal a non-issue. Reading animals as metaphors, always as figures of and for the human, is a process that likewise ends with the human alone on the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Lancet
دوره 378 9787 شماره
صفحات -
تاریخ انتشار 2011